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Duloxetine in the Treatment of Fibromyalgia Clinical Trial

Study Shows Promise of Possible New Treatment for Fibromyalgia

While the Food and Drug Administration (FDA) has not yet approved any treatment protocol for Fibromyalgia, a preliminary study indicates that the serotonin and norepinephrine reuptake inhibitor Duloxetine is effective for the treatment of fibromyalgia -- with or without major depressive disorder.

Fibromyalgia is a complicated disease that doesn't stem from a single cause (etiology). This inability to pinpoint exactly what causes fibromyalgia makes it difficult to determine effective therapy for the illness.

A report in the September issue of Arthritis & Rheumatism tells that the results of one of the largest randomized clinical trials to date, and the only trial to evaluate the impact of comorbid major depressive disorder on treatment response, suggests "that duloxetine improves pain and tenderness, the hallmark characteristics of fibromyalgia." Lead author Lesley M. Arnold, MD from the Duloxetine Fibromyalgia Trial Group further says that "[t]he effect of duloxetine on the reduction of pain appears to be independent of its effect on mood."

Additional information on this study and the report can be found at the Medscape Medical News site.

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