Information on Orthostatic Intolerance (OI), a syndrome characterized by
altered mental activity, fatigue, lightheadedness, and temporary
deficiency of oxygen in the brain (swooning); it is associated with
postural tachycardia (POTS) and disproportionately high plasma
norepinephrine (a hormone and neurotransmitter secreted by the adrenal
medulla and the nerve endings of the sympathetic nervous system to cause
increases in heart rate, blood pressure, and the sugar level of the
blood) concentrations.
Orthostatic Intolerance - Definition, Symptoms, Management,
Prognosis
National Dysautonomia Research Foundation (NDRF) information on
Orthostatic Intolerance. Definition includes an explanation of the
Autonomic Nervous System, and how it compensates on the effect of
gravity as it applies to the distribution of blood.
Orthostatic Hypotension Clinical Trials
A state-by-state index of Orthostatic Hypotension Clinical Trials.
Orthostatic Hypotension
The author of this article Timothy C. Hain, M.D. says that "orthostasis
means upright posture, and hypotension means low blood pressure.
Thus, orthostatic hypotension consists of symptoms of dizziness,
faintness or lightheadedness which appear only on standing, and
which are caused by low blood pressure." The article includes
information on the causes, diagnosis, and treatment for this
condition.
Orthostatic Intolerance: An Overview
Well-documented eMedicine article on Orthostatic Intolerance.
Orthostatic Intolerance in Adolescent Chronic Fatigue Syndrome
The abstract of a New York Medical College study on "Orthostatic
Intolerance in Adolescent Chronic Fatigue Syndrome" with links to
the full text of the article and to other articles that cite this
study.
Orthostatic Intolerance & Tachycardia Associated w/Norepinephrine Def.
The abstract with full text links to a study on "Orthostatic Intolerance
and Tachycardia Associated with Norepinephrine-Transporter Deficiency"
done by John R. Shannon, M.D., Nancy L. Flattem, B.S., Jens Jordan,
M.D., Giris Jacob, M.D., D.Sc., Bonnie K. Black, B.S.N., Italo Biaggioni,
M.D., Randy D. Blakely, Ph.D., and David Robertson, M.D.
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